Utilizing multiple technology platforms, Servesto forms highly responsive teams led by experienced researchers to provide MagHelix™ drug discovery services. According to your specific demands, our scientists supply customized drug discovery strategies to identify lead compounds and preclinical drug candidates.
Modern drug discovery involves the identification of screening hits, medicinal chemistry and optimization of those hits to increase the affinity, selectivity, efficacy/potency, metabolic stability, and oral bioavailability. Servesto adopts optimal strategies to reduce the potential of side effects of drugs or increase the half-life of drugs during drug discovery procedure. The process of looking for a new drug against a specific target for a certain disease commonly involves high-throughput screening (HTS), wherein large libraries of chemicals are tested for their ability to modify the target. For instance, if the target is a novel GPCR, compounds will be screened for their ability to inhibit or stimulate the receptor; if the target is a protein kinase, the chemicals will be tested for their ability to inhibit the kinase.
With strong expertise in medicinal chemistry, biochemistry, molecular and cell biology, our team is dedicated to structural and computational drug design against targets. Our aim is to identify promising hits through screening and further to optimize the preclinical drug candidates. Our drug discovery service can assist your early stage conceptual design, virtual screen and core computational molecular modeling studies. In addition, we can also provide Zebrafish Screening Platform to investigate possible drug-like effects, which prove to be very useful in disease models.
Servesto applies Structure-Activity Relationships (SAR) to improve the features of the lead compound, including:
Servesto provides the following entire pipeline services:
Please feel free to contact us to discuss your project!