Servesto is well-equipped and relies on high-throughput screening technologies for the expression and purification, as well as structural characterization of difficult membrane protein targets, such as GPCRs, ion channels, transporters and GPI-anchored proteins. Our platform supports a variety of membrane protein services that meet user's specific requirements:
- Technical support for choosing appropriate cell-based or cell-free membrane protein production systems
- Membrane protein preparation in native conformation using liposome, virus-like particle (VLP) and nanodisc technologies
- Characterization of membrane protein properties including molecular size, glycosylation sites, isoelectric point (pI), pH stability, temperature stability, ionic strength stability, hydrophobicity, detergent requirement, biospecific affinity, etc.
- Detection of protein-protein interaction
- Structural determination by X-ray crystallography, NMR spectroscopy or cryo-EM
- Servesto is more than happy to be your reliable business associate, please feel free to contact us for a detailed quote.